The seed of the milk thistle plant is commonly used to treat chronic inflammatory liver disorders and it is among the top-selling medicinal herbs.While milk thistle products are easy to come by, this is … Dosing adjustments to diabetes medications might be necessary. Milk thistle seed might protect liver cells from toxic chemicals and drugs. It is fully referenced and updated daily. Jepson Online Interchange for California Flora. ), © 2006-2020 California Invasive Plant Council. The seeds are roasted for use as a coffee substitute. It is a holistic extract formulated with vegetarian capsules using a natural extraction method. If you have any condition that might be made worse by exposure to estrogen, don’t use these extracts. Mapping weeds and rare plants to inform management and conservation in the Zaca and Jesusita fires. Paradise Herbs Milk Thistle is a 100% pure milk thistle supplement. Milk thistle might decrease the effects of estrogen pills by blocking how estrogen works in the body. Natural Medicines rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, Ineffective, and Insufficient Evidence to Rate. Yes, I would like to receive emails from California Invasive Plant Council. Some herbs and supplements that can lower blood sugar include alpha-lipoic acid, bitter melon, chromium, devil’s claw, fenugreek, garlic, guar gum, horse chestnut, Panax ginseng, psyllium, Siberian ginseng, and others. Each milk thistle flower contains dozens of seeds, which soon fall from the plant as the flower head matures, dries, and begins to turn brown. Vomiting can also be a problem caused by the intake of milk thistle. Also known as silymarin marianum: milk thistle is a prickly, purple flowering herb that grows wild in all of the states with mild weather like California and Washington. Milk thistle is an annual, full-sun plant that germinates in late winter in our climate zone (Ag Zone 7b). What other names is the product known by? Therapeutic Research Faculty, publishers of Natural Medicines, Prescriber’s Letter, and Pharmacist’s Letter. Interaction Rating =  Minor Be watchful with this combination. This might decrease how well these medications work. Some medications used for lowering cholesterol include atorvastatin (Lipitor), fluvastatin (Lescol), lovastatin (Mevacor), pravastatin (Pravachol), and rosuvastatin (Crestor). Monitor your blood sugar closely. The liver helps break down these medications. Milk thistle (Silybum marianum) is a perennial herb believed to have medicinal properties. Taking milk thistle might decrease how well the body breaks down raloxifene (Evista) in the intestines. California Gold Nutrition ® Silymarin Complex is a unique formula that includes a blend of Milk Thistle, Dandelion, Artichoke and Turmeric. Though Milk Thistle may be one of the most recognized herbs for Liver support, Dandelion, Artichoke and Turmeric all offer a synergistic effect. Milk thistle is a heady, spiny plant with white-veined leaves and purple flowers. Before taking milk thistle, talk to your healthcare provider if you take any medications that are changed by the liver. Synonyms: Carduus marianus L., Carduus mariae Crantz, Cirsium maculatum Scop., Cathamus maculatum (Scop.) Some medications used for diabetes include glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, metformin (Glucophage), pioglitazone (Actos), rosiglitazone (Avandia), and others. Milk thistle is a plant that is native to Europe and was brought to North America by early colonists. 13770 Noel Road, Suite 801889 Milk thistle extractis LIKELY SAFE when taken by mouth for most adults. California Gold Nutrition EuroHerbs ™ Milk Thistle contains an extract made from the fruit/seeds of European Milk Thistle Extract standardized to 80% Total Silymarin Flavonoids. California Thistle Cirsium occidentale var californicum is a Perennial herb native to the Santa Monica Mountains and endemic to California (i.e. Allergy to ragweed and related plants: Milk thistle may cause an allergic reaction in people who are sensitive to the Asteraceae/Compositae plant family. Site by, Weed biological control agents approved for California, Taking to the air to locate, prioritize and treat effectively, Control of exotic plants in an herbaceous understory. For diabetes: 200 mg of a specific product (Legalon, Madaus GmbH, Cologne, Germany) has been taken three times daily for 4 months to one year. It is widely spread throughout California in overgrazed pastures and along fencelines and other disturbed areas. The flowers are larger and more globe-shaped. The leaves also have unique white markings that, according to legend, were the Virgin Mary’s milk. Milk thistle is a plant that is native to Europe and was brought to North America by early colonists. Medications changed by the liver (Cytochrome P450 3A4 (CYP3A4) substrates). Before taking milk thistle, talk to your healthcare provider if you take any medications that are changed by the liver. The largest infestations in the state are in pastures in the southeastern section of King County but infestations are occasionally found elsewhere. The plant can grow rather tall (3 meters) and has showy pink, purple or white flowers. This might cause more side effects from some medications. The Benefits of Milk Thistle. The following doses have been studied in scientific research: Artichaut Sauvage, Blessed Milk Thistle, Cardo Lechoso, Cardui Mariae Fructus, Cardui Mariae Herba, Carduus Marianum, Carduus marianus, Chardon Argenté, Chardon de Marie, Chardon de Notre-Dame, Chardon Marbré, Chardon-Marie, Épine Blanche, Holy Thistle, Lady’s Thistle, Lait de Notre-Dame, Legalon, Marian Thistle, Mariendistel, Mary Thistle, Our Lady’s Thistle, Shui Fei Ji, Silibinin, Silybe de Marie, Silybin, Silybum, Silybum marianum, Silymarin, Silymarine, St. Mary Thistle, St. Marys Thistle. In California, it is found on the North Coast, North Coast Ranges, Central Valley, San Francisco Bay region, South Coast Ranges, South Coast, and Channel Islands, to about 1600 feet … Some medications are moved by pumps in cells. Using it with other herbs or supplements that have the same effect might cause blood sugar levels to drop too low. Some medications that are changed by the liver include amitriptyline (Elavil), diazepam (Valium), zileuton (Zyflo), celecoxib (Celebrex), diclofenac (Voltaren), fluvastatin (Lescol), glipizide (Glucotrol), ibuprofen (Advil, Motrin), irbesartan (Avapro), losartan (Cozaar), phenytoin (Dilantin), piroxicam (Feldene), tamoxifen (Nolvadex), tolbutamide (Tolinase), torsemide (Demadex), warfarin (Coumadin), and others. Plus dosage, safety, side effects, drug interactions and more. Lam., Silybum maculatum (Scop.) Don’t confuse milk thistle with blessed thistle (Cnicus benedictus). Some of these medications changed by the liver include acetaminophen (Tylenol, others) and oxazepam (Serax), haloperidol (Haldol), lamotrigine (Lamictal), morphine (MS Contin, Roxanol), zidovudine (AZT, Retrovir), and others. Medications moved by pumps in cells (P-Glycoprotein Substrates). There isn’t enough reliable information available to know if milk thistle is safe to apply to the skin or inject into the body. People use milk thistle intravenously (by IV) for Amanita phalloides (death cap) mushroom poisoning. Trying to find the best milk thistle supplements? Medications changed by the liver (Cytochrome P450 3A5 (CYP3A5) substrates). Early detection and rapid, effective response is of the highest priority for this noxious weed. These liver problems include cirrhosis, jaundice, hepatitis, and gallbladder … Silybummarianum is the scientific name of milk thistle is a typical weed grown in California, which is then turned into extract or supplement forming pure milk thistle. Presentations are linked where available. Review information on amounts of silymarin found in popular brands, evidence for liver protection, diabetes and other uses. Interaction Rating = Moderate Be cautious with this combination. Are there any interactions with Herbs and Supplements? Pregnancy and breast-feeding: There is not enough reliable information about the safety of taking milk thistle if you are pregnant or breast feeding. Milk thistle is taken by mouth most often for liver disorders, including liver damage caused by chemicals, alcohol, and chemotherapy, as well as liver damage caused by Amanita phalloides (death cap) mushroom poisoning, nonalcoholic fatty liver disease, chronic inflammatory liver disease, cirrhosis of the liver, and chronic hepatitis. Some people apply milk thistle directly to the skin for skin toxicity caused by radiation. Indinavir (Reyataz) is a drug that is changed and broken down by the liver. Plant Assessment Form - Information gathered by Cal-IPC on the impacts, rate of spread, and distribution of invasive plants in California. For the latest comprehensive data on this and every other natural medicine, health professionals should consult the Professional Version of the Natural Medicines. California Gold Nutrition, Silymarin Complex, Milk Thistle Extract Plus, 300 mg, 120 Veggie Capsules Serving Size: 1 Veggie Capsule Servings Per Container: 120 Silymarin Milk Thistle Extract is a flowering herb that helps support healthy liver function. Milk thistle is a plant named for the white veins on its large prickly leaves.One of the active ingredients in milk thistle is silymarin, which is extracted from the plant's seeds. It is not only edible, but good for you—it's just a little hard to disarm. Effort is made to ensure that the information contained in this monograph is accurate at the time it was published. Some medications that are moved by these pumps include etoposide, paclitaxel, vinblastine, vincristine, vindesine, ketoconazole, itraconazole, amprenavir, indinavir, nelfinavir, saquinavir, cimetidine, ranitidine, diltiazem, verapamil, digoxin, corticosteroids, erythromycin, cisapride (Propulsid), fexofenadine (Allegra), cyclosporine, loperamide (Imodium), quinidine, and others. 1-877-465-66361-877 GO KOMEN, For breast health or breast cancer information, please call the Breast Care Helpline: 1-877-465-6636 or helpline@komen.org, For clinical trial information, please call the Clinical Trial Information Helpline: 1-877-465-6636 or clinicaltrialinfo@komen.org, © 2020 Susan G. Komen is a 501(c)(3) non-profit organization. Milk thistle (Silybum marianum), also called holy thistle and lady's thistle, is a common weed in California, but grows throughout the world in climate zones 5 through 9.The plant has purple to red flowers and can be up to 10 feet tall. Other less common side effects are nausea, diarrhea, indigestion, intestinal gas, bloating, fullness or pain, and loss of appetite. This might increase the effects and side effects of tamoxifen (Nolvadex). Milk thistle (also called silybum milk thistle) is a tricky plant. Taking milk thistle along with some medications that are broken down by the liver might increase the effects and side effects of these medications. The extract is standardized to 80% silymarin and is free from common allergens. The plant grows up to 2 meters high and has large, bright purple flowers. Find out which ones passed our tests and why. The above ground parts and seeds are used to make medicine. If you have allergies, be sure to check with your healthcare provider before taking milk thistle. Some medications that are changed by the liver include clozapine (Clozaril), cyclobenzaprine (Flexeril), fluvoxamine (Luvox), haloperidol (Haldol), imipramine (Tofranil), mexiletine (Mexitil), olanzapine (Zyprexa), pentazocine (Talwin), propranolol (Inderal), tacrine (Cognex), theophylline, zileuton (Zyflo), zolmitriptan (Zomig), and others. Blessed milkthistle is a common winter or summer annual or biennial broadleaf plant. The plant grows up to 2 meters high and has large, bright purple flowers. Theoretically, milk thistle might change the levels of some medications used for lowering cholesterol (statins). milk. (and also proven to be 10x more bioavailable than just the milk thistle extract itself)Each serving comes with 80 mg of milk thistle extract, but because of its formulation, you get … It is widely spread throughout California in overgrazed pastures and along fencelines and other disturbed areas. In the United States, milk thistle is grown throughout California and the western states. Some estrogen pills include conjugated equine estrogens (Premarin), ethinyl estradiol, estradiol, and others. Milk thistle is native to Europe and was introduced into North America by early colonists. Blessed milk thistle produces tall, … This is a walk to view the various life stages of Milk Thistle as it appears on our property. The largest specimens have hollow stems. Moench, Silybum mariae (Crantz) Gray, Mariana lactea Hill, Common names: milk thistle; variegated thistle; blessed milk thistle; Virgin Mary's thistle; Lady's milk; Holy thistle; spotted thistle; cabbage thistle; spotted thistle; St. Mary's thistle; white thistle. Milk thistle might increase how quickly the liver breaks down some medications. 200 mg of a different silymarin product (Luna Co., Cairo, Egypt) has been daily for 120 days. The extract of this herb is used to reap its cell regenerating benefits. Studies vary in the dosage of milk thistle used. It is also free from fillers, flows, fractionalizing gases, and harsh chemicals. Milk thistle might increase how much tamoxifen (Nolvadex) is absorbed by the body. Milk thistle might affect how quickly the liver breaks down some medications. Silymarin bound to phosphatidylcholine, a milk thistle supplement, tends to be better absorbed by the body than other preparations. The stem is grooved and may be covered in a light cottony fuzz. Consumers and medical professionals who consult this monograph are cautioned that any medical or product related decision is the sole responsibility of the consumer and/or the health care professional. But milk thistle does not seem to affect how quickly the body breaks down indinavir (Reyataz). Milk thistle is a weed, which grows commonly in California and other parts of the world having a warm climate. The dose of your diabetes medication might need to be changed. It also seems to have antioxidant and anti-inflammatory effects. Milk thistle is sometimes used as a natural treatment for liver problems. The seeds are more commonly used. Reliably reducing milk thistle (Silybum marianum) to zero density: a treatment model for annual weeds with plastic life cycles. Susan G. Komen Before taking milk thistle, talk to your healthcare provider if you are taking tamoxifen (Nolvadex). Some medications changed by the liver include lovastatin (Mevacor), ketoconazole (Nizoral), itraconazole (Sporanox), fexofenadine (Allegra), triazolam (Halcion), alprazolam (Xanax), amlodipine (Norvasc), clarithromycin (Biaxin), cyclosporine (Sandimmune), erythromycin, verapamil (Calan, Isoptin) and many others. © Copyright 1995-2019. Before taking milk thistle, talk to your healthcare provider if you are taking raloxifene (Evista). Milk thistle gets its name from the milky sap that comes out of the leaves when they are broken. Prickly yet pretty, milk thistle is a plant with a long, thin stem, spiny leaves, and a purplish-pink thistle at the top. Milk thistle is an annual plant native to southern Europe and Asia, but today it is found all over the world. In contrast, the more commonly used milk thistle SEED extracts do not seem to act like estrogen. People mainly use the supplement to treat liver conditions. (You can unsubscribe anytime. This field is for validation purposes and should be left unchanged. Diabetes: Certain chemicals in milk thistle might lower blood sugar in people with diabetes. Are there any interactions with medications? It leads to the loss of appetite which leads to weakness. How to grow milk thistle from seed. Loss of Appetite: This is another effect of milk thistle caused in the body. This might increase the effects and side effects of sirolimus (Rapamune). California reports milk thistle stands of up to 4 tons per acre in heavily infested areas. EIN 75-1835298. Milk thistle (Silybum marianum) can look a lot like Italian thistle, especially as a seedling. Milk thistle sometimes causes a laxative effect. Some people also take milk thistle by mouth for diabetes, kidney damage caused by diabetes or contrast media use, prostate cancer, to decrease the side effects of chemotherapy and radiation, uterine complaints, increasing breast milk flow, allergy symptoms, starting menstrual flow, obsessive-compulsive disorder (OCD), Alzheimer’s disease, Parkinson’s disease, multiple sclerosis (MS), high cholesterol, and menopausal symptoms. Prized for its medicinal properties, it is also considered highly invasive and is being targeted for eradication in some areas. Some medications are changed and broken down by the liver. Before taking milk thistle, talk to your healthcare provider if you are taking sirolimus (Rapamune). The Effectiveness ratings for Milk Thistle are as follows: Insufficient Evidence to Rate Effectiveness for…. Milk thistle is an herbal remedy derived from the milk thistle plant, also known as Silybum marianum. The terms “milk thistle” and “silymarin” are often used interchangeably. Taking milk thistle might affect how well the liver breaks down drugs. This amazing natural remedy is being used for more than 2,000 years and people can experience immediate results. The stomach might get upset frequently. Medications for diabetes (Antidiabetes drugs). In foods, milk thistle leaves and flowers are eaten as a vegetable for salads and a substitute for spinach. Milk Thistle (Silybum Marianum) Milk thistle, or Silybum Marianum, is a commonly used herbal medicine in the management of several disorders. Members of this family include ragweed, chrysanthemums, marigolds, daisies, and many others. This might increase or decrease how well some of these medications work. Taking milk thistle along with some medications that are broken down by the liver might increase or decrease the effects of these medications. Click here for the lowest priceWhen it comes to your liver, you do not want to mess around.LiverMD is a premium choice, but its worth it because of its patented version of milk thistle that was specifically developed to improve its absorption into your body. In this video I came across some to the Red Milk Thistle plants that i really liked back in the southern parts of california. Milk thistle is now found throughout the eastern United States, California, South America, Africa, Australia, and Asia. Milk thistle is also taken by mouth for heartburn (dyspepsia), inflammatory bowel disease (ulcerative colitis), enlarged prostate (benign prostatic hyperplasia), a blood disorder called beta-thalassemia, and infertility. Some medications changed by the liver include testosterone, progesterone (Endometrin, Prometrium), nifedipine (Adalat CC, Procardia XL), cyclosporine (Sandimmune), and others. Stay on the safe side and avoid use. The approximate maximum base diameter is 160 cm (63 in). Milk thistle can lower blood glucose levels. Medications changed by the liver (Cytochrome P450 2D6 (CYP2D6) substrates). According to the University of California-San Diego, a reasonable therapeutic dosage might be about 420 mg to 500 mg of a standardized milk thistle extract per day. For upset stomach (dyspepsia): 1 mL of a specific combination product (Iberogast, Medical Futures, Inc) containing milk thistle and several other herbs has been used three times daily for 4 weeks. Natural Medicines disclaims any responsibility related to medical consequences of using any medical product. Also called silybum, the name milk thistle comes from an ancient legend that says the white, vein-like spots on the rich green leaves were made when the Virgin Mary fled Egypt while nursing her child. It flowers and goes to seed from May – early June, after which the plants die. Milk thistle might make these pumps less active and increase how much of some medications get absorbed by the body. Some medications are changed and broken down by the liver. A legal License Agreement sets limitations on downloading, storing, or printing content from this Database. Where a presentation is not available, find more information by reading the abstract in the Cal-IPC Symposia Archive. Taking milk thistle might decrease how well the liver breaks down sirolimus (Rapamune). We won't sell or give away your email address. The seeds contain silymarin, a group of compounds said to have antioxidant and anti-inflammatory effects. Medications changed by the liver (Glucuronidated drugs). Created on October 31, 2011 in Templeton, California. Medications used for lowering cholesterol (Statins). But its leaves are not as deeply lobed, the milky stripes are much more pronounced, and the plant grows much bigger and more robust. Dallas, TX 75380, helpline@komen.org Complementary and Integrative Therapies References. More evidence is needed to rate the effectiveness of milk thistle for these uses. Intake of milk thistle causes diarrhea which can further lead to other serious problems. Milk thistle california. He persuaded the Food and Drug Administration to allow its use as an emergency investigational new drug. Milk thistle is an upright herb which can grow to be 30 to 200 cm (12 to 79 in) tall, and have an overall conical shape. The body breaks down some medications to get rid of them. This might increase the effects and side effects of raloxifene (Evista). The milk thistle is the plant with the variegated leaves with milky white veins. Unlawful to download, store, or distribute content from this site. Hormone-sensitive conditions such as breast cancer, uterine cancer, ovarian cancer, endometriosis, or uterine fibroids: Extracts from milk thistle PLANT might act like estrogen. EuroMed is the world's leading manufacturer of Milk Thistle extract and uses elite seed cultivators to produce a high quality, clinically tested product. Milk thistle is commonly used as a home remedy to treat liver problems, often under the presumption that it will "detoxify" the liver. Blessed milk thistle produces tall, dense stands that outcompete native species. Except for any possible exceptions written into your License Agreement, no reproduction of this monograph or any content from this Database is permitted without written permission from the publisher. Other parts of this wild plant, beside the seeds, are also edible. Medications changed by the liver (Cytochrome P450 1A2 (CYP1A2) substrates). Milk thistle is found throughout the eastern United States, California, South America, Africa, Australia, and Asia. For more than 2,000 years, milk thistle has been used as a medicinal herb in traditional wellness practices. Silybum marianum (blessed milk thistle) is a winter annual or biennial with prickly leaves (family Asteraceae). Milk thistle can lower blood sugar levels. Interaction Rating = Minor Be watchful with this combination. Find more information by reading the abstract in the Zaca and Jesusita.! €¦ milk thistle is sometimes used as a natural extraction method you will be to... Medications changed by the liver ( Cytochrome P450 3A4 ( CYP3A4 ) substrates ) vegetarian capsules using natural... By the liver ( Cytochrome P450 2D6 ( CYP2D6 ) substrates ) extract formulated with vegetarian using..., artichoke and Turmeric in our climate zone ( Ag zone 7b ) with thistle... Estradiol, estradiol, and harsh chemicals get absorbed by the body breaks down.... 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